ORIGINAL SCIENTIFIC ARTICLES  (Peer Reviewed):
Note:  *Asterisks indicate publications where Dr. Frisina’s trainee is an author (name italicized). 

*D’Souza, M., Zhu, X., Frisina, R.D. (2015- In Prep) Co-expression of GABA vesicular transporter member1, Slc32a1, with GABA B receptor 1, Gabbr1, in the auditory midbrain of aging mice.

Ding, B., J.P. Walton, X. Zhu, R.D. Frisina.  (2015 – In Prep) Subunit Isoform Selectivity and Age-Related Expression Changes of Na, K-ATPase in the Mouse Cochlear Stria Vascularis.

Halonen, J., Hinton, A., Frisina, R.D., Zhu, X., Walton, J.P. (2015 – Submitted) Long-term Treatment with the Mineralocorticoid Aldosterone Slows Down the Progression of Age-Related Hearing Loss Measured Behaviorally.

Antoine, M.W., Zhu, X., Vijayakumar, S., Arezzo, J.C., McKeehan, N., Zukin, R.S., Borkholder, D., Jones, S., Frisina, R.D., Hébert, J.M.  (2015 – In Prep) Atypical cerebral lateralization as a consequence of early inner ear dysfunction.   

Frisina^, R.D., Ding^, B., X. Zhu, J.P. Walton (2015– Submitted) A Medical Treatment for Permanent Hearing Loss: Aldosterone can Slow Down the Progression of Age-related Hearing Impairment – Presbycusis. ^equal 1st authors.

Frisina^, R.D., H.E. Wheeler^, S.D. Fossa, S. Kerns, H.D. Sesso, D.R. Feldman, R. Hamilton, D.J. Vaughn, C.J. Beard, C. Fung, A. Budnick, A. Weinzerl, E. Johnson, L.H. Einhorn, N.J. Cox, M.E Dolan, L.B. Travis.  (2015 – In Prep)  Comprehensive Characterization of Cisplatin-Related Hearing Loss and Tinnitus: Implications for Improved Management and Therapeutics.  ^equal 1st authors.

*Kim, S-H., K. Jeong, D.R. Frisina, R.D. Frisina (2015- Submitted) The Right-Ear Advantage in the Hearing-in-Noise Test: The Effects of Age and Hearing Loss.

*Williamson, T.T., Zhu, X., Walton, J.P., Frisina, R.D. (2015) Auditory Brainstem Gap Responses Start to Decline in Middle Age Mice: A Novel Physiological Biomarker for Age-Related Hearing Loss.  Cell & Tissue Research. 361, 359-369. [Impact Factor ~4]

Travis, L.B., Fossa, S.D.,  Sesso, H.D., Frisina, R.D., Herrmann, D.N., Beard, C.J., Feldman, D.R., Pagliaro, L.C., Miller, R.C., Vaughn, D.J., Einhorn, L.H., Cox, N.J., Dolan, M.E. (2014) Chemotherapy-Induced Peripheral Neuropathy and Ototoxicity:  A Paradigm for Translational Genomics. J. Nat. Cancer Inst. 106(5):  1-11. [Impact Factor ~14]

*Tadros, S.F., D’Souza, M., Zhu, X., Frisina, R.D. (2014) Age-related gene expression changes for antioxidants in the CBA mouse cochlea. Plos One. 9:e90279, 1-9. [Impact Factor ~4]

*Tang, X., Zhu, X., Ding, B., Walton, J.P., Frisina, R.D., Su, J.(2014) Age-related Hearing Loss: GABA, Nicotinic acetylcholine and NMDA Receptor Expression Changes in Spiral Ganglion Neurons of the Mouse Cochlea. Neuroscience. 259, 184-193. [Impact Factor ~3]

*Ding, B., R.D. Frisina, X. Zhu, Y. Sakai, B. Sokolowski, J.P. Walton (2014) Direct control of Na+-K+-2Cl- co-transport protein (NKCC1) expression with aldosterone.  Am. J. Physiol.- Cell Physiol. Endocrinol. Metabolism. 306 (1): C66-75. (PMID: 24173102) [Impact Factor ~4]

Borkholder, D.A., Zhu, X., Frisina, R.D. (2014) Round Window Membrane Intracochlear Drug Delivery Enhanced by Induced Advection. J. Controlled Release. 174:171–176. [Impact Factor ~8]

*Haghpanahia, M., Gladstone, M.B., Zhu, X., Frisina, R.D., Borkholder, D.A. (2013) Noninvasive Quantification of Transport through the Murine Cochlea Using Micro-Computed Tomography.  Annals Biomedical Engineering. 41: 2130-2142. [Impact Factor ~3]

Zecker, S.G., H. Hoffman, R.D. Frisina, J. R. Dubno, S. Dhar, M. Wallhagen, Ph.D., N. Kraus, J. W. Griffith, J. P. Walton, D. A. Eddins, C. Newman, Ph.D., D. Victorson, C. M. Warrier, R. H. Wilson. (2013)  Audition Assessment Using the NIH Toolbox. Neurology.  80(11 Suppl. 3):S45-48.

Newman, D.L., Fisher, L.M, Ohmen, J., Parody, R., Fong, C-T., Frisina, S.T., Mapes, F., Eddins, D.A., Frisina, D.R., Frisina, R.D., Friedman, R.A.  (2012) GRM7 association with age-related hearing loss and its extension to additional features of presbycusis. Hear. Res. 294: 125-132. [Impact Factor ~3]

* Frisina, R.D., Singh, A., Bak, M., Bozorg, S., Seth, R., Zhu, X. (2011) F1 (CBA x C57) mice show superior hearing in old age relative to their parental strains: Hybrid vigor or a new animal model for "Golden Ears"?  Neurobiology of Aging. 32: 1716-1724. (PMCID:  PMC2891213) [Impact Factor ~6]

*Tra, Y., Frisina, R.D., D’Souza, M., (2011) A novel high-throughput analysis approach:  Immune response-related genes are up-regulated in age-related hearing loss. Open Access Bioinformatics3: 1-16.

Margolis, R.H., Frisina, R.D., Walton, J.P.  (2011)  AMTAS® - Automated Method for Testing Auditory Sensitivity:  III. Air Conduction Audiograms in Children and Adults.  International J. of Audiology. 50: 434-439. (PMID: 21417674)

Johnson, D.G., Frisina, R.D., Borkholder, D.A.  (2011) In-Plane Biocompatible Microfluidic Interconnects for Implantable Microsystems.  IEEE Transactions on Biomedical Engineering. 58: 943-948. (PMID: 21147591)

Johnson, D.G., Waldron, M.J., Frisina, R.D., Borkholder, D.A. (2010) Implantable Micropump Technologies for Murine Intracochlear Infusions.  IEEE Engineering in Medicine and Biology Society. 6441-6444. (PMID: 21096713; PMCID: PMC3137522)

*Charitidi, K., Frisina, R.D., Vasilyeva, O.N., Zhu, X., Canlon, B.  (2010) Expression patterns of estrogen receptors in the central auditory system change in prepubertal and aged mice.  Neuroscience. 170: 1270-1281. (PMID: 20736049; PMCID: PMC3133947) [Impact Factor ~3]

*Borkholder, D.A., Zhu, X., Hyatt, B.T., Archilla, A.S., Livingston, W.J., Frisina, R.D.  (2010)  Murine Intracochlear Drug Delivery: Reducing Concentration Gradients within the Cochlea. Hearing Res. 268: 2-11. (PMID: 20451593; PMCID: PMC2933796) [Impact Factor ~3]

Frisina, R.D., Zhu, X.  (2010)  Auditory sensitivity and the outer hair cell system in the CBA mouse model of age-related hearing loss.  Open Access Animal Physiology. 2: 9-16.  (PMCID: PMC3159169)

*Polesskaya, O., Cunningham, L.L., Francis, S.P., Luebke, A.E., Zhu, X., Collins, D., Vasilyeva, O.N.,  Sahler, J., Desmet, E.A., Gelbard, H.A., Maggirwara, S.B., Walton, J.P., Frisina, R.D., Dewhurst, S.  (2010).   Ablation of mixed lineage kinase 3 (Mlk3) does not inhibit ototoxicity induced by acoustic trauma or aminoglycoside exposure. Hearing Res. 270, 21-27.  (PMID: 20971179; PMCID: PMC2997883) [Impact Factor ~3]

*Christensen, N., D’Souza, M., Zhu, X., Frisina, R.D. (2009) Age-related hearing loss: Aquaporin 4 gene expression changes in the mouse cochlea and auditory midbrain. Brain Res. 1253: 27-34. (PMCID: PMC2670229)

*Price, K., Zhu, X., Guimaraes, P., Vasilyeva, O.N., Frisina, R.D.  (2009)  Hormone replacement therapy diminishes hearing in perimenopausal mice. Hearing Res. 252: 29-36. (PMCID: PMC2698030) [Impact Factor ~3]

*Vasilyeva, O.N., Frisina, S.T., Zhu, X., Walton J. P., Frisina, R.D. (2009) Interactions of hearing loss and Diabetes Mellitus in the CBA/CaJ mouse model of presbycusis.  Hearing Res. 249:  44-53.  (PMCID: PMC2891295) [Impact Factor ~3]

*Tadros, S.F., D’Souza, M., Zhu, X., Frisina, R.D. (2008).  Apoptosis-related genes change their expression with age and hearing loss in the mouse cochlea. Apoptosis 13: 1303-1321. (PMCID: PMC2829878) [Impact Factor ~4]

*D’Souza, M., Zhu, X., Frisina, R.D. (2008) Novel Approach for Selecting Genes from RMA Normalized Microarray Data Using Functional Hearing Tests in Aging Mice. J. Neuroscience Methods, 171:279-287. (PMCID: PMC2440495)

Johnson, D.G., Zhu, X., Frisina, R.D., Borkholder, D.A. (2007) Micro-Molded Cannulae for Intracochlear Infusions in Small Rodents.  29th IEEE EMBS Annual International Conf. Proc.: Medicine & Biology, 6616-6619.

*Frisina, R.D., Newman, S.R., Zhu, X. (2007) Auditory efferent activation in CBA mice exceeds that of C57s for varying levels of noise. J. Acoustical Society of America, 121: EL-29-34.

Zettel, M.L., Zhu, X., O’Neill, W.E., Frisina, R.D. (2007) Age-related Declines in Kv 3.1b Expression in the Mouse Auditory Brainstem Correlate with Functional Deficits in the Medial Olivocochlear Efferent System.  J. Assoc. Res. Otolaryngology – JARO, 8:280-293.  (PMCID: PMC2538355) . [Impact Factor ~3]

*Tadros, S.F., D’Souza, M., Zettel, M.L., Zhu, X., Lynch-Erhardt, M., Frisina, R.D. (2007) Serotonin 2B Receptor: Upregulated with Age and Hearing Loss in Mouse Auditory System. Neurobiology of Aging, 28:1112-1123. [Impact Factor ~6]

*Zhu, X., Vasilyeva, O.N., Kim, S-H., Jacobson, M., Romney, J., Waterman, M.S., Tuttle, D., Frisina, R.D. (2007) Auditory efferent system declines precede age-related hearing loss: Contralateral suppression of otoacoustic emissions in mice. J. Comparative Neurology, 503: 593-604. [Impact Factor ~4]

*Tadros, S.F., D’Souza, M., Zettel, M.L., Zhu, X., Waxmonsky, N.C., Frisina, R.D. (2007) Glutamate-related gene expression in CBA mouse inferior colliculus changes with age and hearing loss.  Brain Res. 1127: 1-9. (PMCID: PMC2423939)

*Kim, S-H., Frisina, R.D., Frisina, S.T., Mapes, F.M., Hickman, E.D., Frisina, D.R. (2007) Effects of Age and High-Frequency Hearing Loss on Binaural Speech Understanding using HINT. J. Acoust. Soc. (Korea). 26:1-7.

*Guimaraes, P., Frisina, S.T., Mapes, F., Tadros, S.F., Frisina, D.R., Frisina, R.D. (2006) Progestin Negatively Affects Hearing in Aged Women. Proc. National Academy Sciences - PNAS. 103: 14246-9.  (PMCID: PMC1560930) [Impact Factor ~10]

Frisina, R.D., Walton, J.P. (2006) Age-Related Structural and Functional Changes in the Cochlear Nucleus. Hearing Res. 217:216-233.  [Impact Factor ~3]

*Thompson, S.K., Zhu, X., Frisina, R.D. (2006) Estrogen Blockade Reduces Auditory Feedback in CBA Mice. Otolaryngology- Head & Neck Surgery. 135:100-105.

*Kim, S-H., Frisina, R.D., Mapes, F.M., Hickman, E.D., Frisina, D.R. (2006) Effect of Age on Binaural Speech Intelligibility in Normal Hearing Adults. Speech Communication. 48:591-597.

*Frisina, S.T., Mapes, F., Kim, S-H., Frisina, D.R., Frisina, R.D.  (2006) Characterization of Hearing Loss in Aged Type II Diabetics. Hearing Res. 211:103-113. (PMCID: PMC2745069) [Impact Factor ~3]

*Tadros, S.F., Frisina, S.T., Mapes, F., Frisina, D.R., Frisina, R.D. (2005) High Serum Aldosterone Levels Correlate with Lower Hearing Thresholds in Aged Humans: A Possible Protective Hormone against Presbycusis.  Hearing Res. 209:10-18. [Impact Factor ~3]

*Varghese, G.I., Zhu, X., Frisina, R.D. (2005) Age-Related Declines in Contralateral Suppression of Distortion Product Otoacoustic Emissions Utilizing Pure Tones in CBA/CaJ Mice. Hearing Res. 209:60-67. [Impact Factor ~3]

*Tadros, S., Frisina, S.T., Mapes, F., Kim, S-H., Frisina, D.R., Frisina, R.D. (2005) Loss of Peripheral Right Ear Advantage in Age-Related Hearing Loss.  Audiology & Neuro-Otology, 10:44-52.

Simon, H., Frisina, R.D. and Walton, J.P. (2004) Age reduces response latency of mouse inferior colliculus neurons to AM sounds. J. Acoustical Society of America 116:469-477.

Xiao, Y., Frisina, R.D., Gordon, A., Klebanov, L., Yakovlev, A. (2004) Multivariate Search for Differentially Expressed Gene Combinations. BMC Bioinformatics, 5:164-184. [Impact Factor ~3]

*Guimaraes, P., Zhu, X., Cannon, T., Kim, S-H., Frisina, R.D. (2004) Sex Differences in Distortion Product Otoacoustic Emissions as a Function of Age in CBA Mice.  Hearing Res.  192:83-89. [Impact Factor ~3]

*Zettel, M.L., Trang, T.T., O’Neill, W.E. and Frisina, R.D. (2003) Activity-dependent age-related regulation of calcium-binding proteins in the mouse dorsal cochlear nucleus.  Hearing Res. 183:57-66.  [Impact Factor ~3]

*Jacobson M., Kim SH., Romney J., Zhu X., Frisina R.D. (2003) Contralateral suppression of distortion-product otoacoustic emissions declines with age: A comparison of findings in CBA mice with human listeners. Laryngoscope. 113:1707-1713.

*Bowers, W.J., Chen, X., Guo, H., Frisina, D.R., Federoff, H.J., Frisina, R.D. (2002) Neurotrophin-3 transduction attenuates cisplatin spiral ganglion neuron ototoxicity in the cochlea.  Molecular Therapy 6:12-18. [Impact Factor ~7]

Salvi, R. J., Lockwood, A. H., Frisina, R. D., Coad, M. L., Wack D. S., Frisina, D.R.  (2002)  PET imaging of the normal human auditory system: Responses to speech in quiet and in background noise.  Hearing Res. 170:96-106.  [Impact Factor ~3]

*Kim, S.H., Frisina, D.R., Frisina, R.D.  (2002) Effects of age on contralateral suppression of distortion-product otoacoustic emissions in human listeners with normal hearing.  Audiol. Neuro-Otol. 7: 348-357.

Walton, J.P., Simon, H., Frisina, R.D. (2002) Age-related alterations in the neural coding of envelope periodicities.  J. Neurophysiology 88: 565-578. [Impact Factor ~4]

Frisina, R.D. (2001) Subcortical neural coding mechanisms for auditory temporal processing.  Hearing Res. 158:1-27.  [Impact Factor ~3; in the top 10 all-time most-cited reviews for this journal]

*Chen, X., Frisina, R.D., Bowers, W.J., Frisina, D.R., Federoff, H.J. (2001) HSV Amplicon-mediated neurotrophin-3 expression protects murine spiral ganglion neurons from cisplatin-induced damage.  Molecular Therapy 3:958-963. [Impact Factor ~7]

*Zettel, M.L., O'Neill, W.E., Trang, T.T. & Frisina, R.D. (2001) Early bilateral deafening prevents calretinin up-regulation in the dorsal cortex of the inferior colliculus of aged CBA/CaJ mice. Hearing Res. 158:131-138.  [Impact Factor ~3]

*Frisina, R.D., Walton, J.P., Lynch-Armour, M.A. & Byrd, J.D.  Inputs to a physiologically-characterized region of the inferior colliculus of the young adult CBA mouse.  Hearing Res. 115, 61-81 (1998).  [Impact Factor ~3]

Walton, J.P., Frisina, R.D. & O’Neill, W.E.  Age-related alteration in neural processing of silent gaps in the central nucleus of the inferior colliculus in the CBA mouse model of presbycusis.  J. Neuroscience 18, 2764-2776 (1998). [Impact Factor ~7]

*O’Neill, W.E., Zettel, M.L., Whittemore, K.R. & Frisina, R.D.  Calbindin D-28k immunoreactivity in the medial nucleus of the trapezoid body declines with age in C57B1/6J, but not CBA/CaJ mice.  Hearing Res. 112, 158-166 (1997).  [Impact Factor ~3]

Walton, J.P., Frisina, R.D., Ison, J.E., & O’Neill, W.E.  Neural correlates of behavioral gap detection in the inferior colliculus of the young CBA mouse.  J. Comparative Physiology A. 181, 161-176 (1997).

Spongr, V.P., Flood, D.G., Frisina, R.D. & Salvi, R.J.  Quantitative measures of hair cell loss in CBA and C57B1/6 mice throughout their life spans.  J. Acoustical Society of America 101, 3546-3553 (1997).

Zettel, M.L., Frisina, R.D., Haider, S. & O’Neill, W.E.  Age-related changes in the immunoreactivity of calbindin D28K and calretinin in the inferior colliculus of the CBA/J and C57/6J mouse.  J. Comparative Neurology 386, 92-110 (1997).  [Impact Factor ~4]

Frisina, D.R. & Frisina, R.D.  Speech recognition in noise and presbycusis:  Relations to possible neural sites.  Hearing Res. 106, 95-104 (1997).  [Impact Factor ~3]

*Frisina, R.D., Walton, J.P., Lynch-Armour, M.A. & Klotz, D.  Outputs of a functionally-characterized region of the inferior colliculus of the young adult CBA mouse model of presbycusis.  J. Acoustical Society of America 101, 2741-2753 (1997).

*Frisina, R.D., Karcich, K.J., Tracy, T., Sullivan, D.M., Walton, J.P. & Colombo, J.   Preservation of amplitude modulation coding in the presence of background noise by chinchilla auditory-nerve fibers. J. Acoustical Society of America 99, 475-490 (1996).

*Walton, J.P., Frisina, R.D. & Meierhans, L.R.  Sensorineural hearing loss effects recovery from short term adaptation in the CBA and C57 mouse models of presbycusis.  Hearing Res. 88, 19-26 (1995).  [Impact Factor ~3]

*Frisina, R.D., Zettel, M.L., Walton, J.P. & Kelley, P.E.  Distribution of calbindin D28k immunoreactivity in the cochlear nucleus of the young adult chinchilla.  Hearing Res., 85, 53-68 (1995). [Impact Factor ~3]

Frisina, R.D., Walton, J.P. & Karcich, K.J.  Dorsal cochlear nucleus single neurons can enhance temporal processing capabilities in background noise.  Experimental Brain Res. 102, 160-164 (1994).

*Crummer, G.C., Walton, J.P., Wayman, J.W., Hantz, E.C. & Frisina, R.D.  Neural processing of musical stimuli by musicians, non-musicians and musicians possessing absolute pitch.  J. Acoustical Society of America, 95, 2720-2727, (1994).

*Swartz, K.P., Walton, J.P., Hantz, E.C., Goldhammer, E., Crummer, G.C. & Frisina, R.D.  P3 event-related potentials and performance of young and old subjects for music perception tasks.  International J. Neuroscience 78, 223-239 (1994).

*Quatela, V.C., Futran, N.D. & Frisina, R.D.  Effects of cyanoacrylate tissue adhesives on cartilage graft viability.  Laryngoscope, 103, 798-803 (1993).

*Kelley, P., Frisina, R.D., Zettel, M.L. & Walton, J.P. Differential calbindin immunoreactivity in the brainstem auditory system of the chinchilla. J. Comparative Neurology, 320, 196-212 (1992).  [Impact Factor ~4]

*Wayman, J., Frisina, R.D., Crummer, G.C., Hantz, E.C. & Walton, J.P.  Effects of musical training and absolute pitch ability on event-related activity in response to sine tones. J. Acoustical Society of America, 91, 3527-3531 (1992).

*Hantz, E.C., Crummer, G.C., Wayman, J.W., Walton, J.P. & Frisina, R.D. Effects of musical training and absolute pitch on the neural processing of melodic intervals: A P3 event-related potential study.  Music Perception, 10, 25-42 (1992).

*Swartz, K.P., Walton, J.P., Crummer, G.C., Hantz, E.C. & Frisina, R.D.  P3 event-related potentials and performance of healthy old and Alzheimer's dementia subjects for music perception tasks. Psychomusicol. 11, 96-118 (1992).

Frisina, R.D., Smith, R.L. & Chamberlain, S.C.  Encoding of amplitude modulation in the gerbil cochlear nucleus: I. A hierarchy of enhancement.  Hearing Res. 44, 99-122 (1990). [Impact Factor ~3]

Frisina, R.D., Smith, R.L. & Chamberlain, S.C.  Encoding of amplitude modulation in the gerbil cochlear nucleus: II. Possible neural mechanisms.  Hearing Res. 44 123-142 (1990). [Impact Factor ~3]

*Lesser, H.D., O'Neill, W.E., Frisina, R.D. & Emerson, R.C.  Do ON-Off units in the mustached bat inferior colliculus prefer "Acoustic Glint" to fluttering targets?  Experimental Brain Res. 82, 137-148 (1990).

*Frisina, R.D., O'Neill, W.E. & Zettel, M.L.  Functional organization of mustached bat inferior colliculus. II. Connections of the FM2 region.  J. Comparative Neurology, 284, 85-107 (1989). [Impact Factor ~4]

*O'Neill, W.E., Frisina, R.D. & Gooler, D.M.  Functional organization of mustached bat inferior colliculus.  I. Representation of FM frequencies important for target ranging revealed by 14C-2-deoxyglucose autoradiography & single unit studies.  J. Comparative Neurology, 284, 60-84 (1989). [Impact Factor ~4]

Frisina, R.D., Walton, J.P. & Crummer, G.C.  Neural basis for music cognition: Neurophysiological foundations.  Psychomusicol. 7, 99-107 (1988).

*Crummer, G.C. Hantz, E., Chuang, S.W., Frisina, R.D. & Walton, J.P.  Neural basis for music cognition: Initial experimental findings.  Psychomusicol. 7 117-126 (1988).

*Walton, J.P., Frisina, R.D., Hantz, E., Swartz, K.P. & Crummer, G.C.  Neural basis for music cognition:  Biomedical implications and future directions.  Psychomusicol. 7, 127-138 (1988).

Frisina, R.D., Smith, R.L. & Chamberlain, S.C.  Differential encoding of rapid changes in sound amplitude by second-order auditory neurons.  Experimental Brain Res. 60, 417-422 (1985).

Smith, R.L., Brachman, M.L. & Frisina, R.D.  Sensitivity of auditory-nerve fibers to changes in intensity:  A dichotomy between decrements and increments.  J. Acoustical Society of America, 78, 1310-1316 (1985).

Frisina, R.D. Chamberlain, S.C., Brachman, M.L. & Smith, R.L. Anatomy and physiology of the gerbil cochlear nucleus: An improved surgical approach for microelectrode studies.  Hearing Res. 6, 259-275 (1982).

Gescheider, G.A., Capraro, A.J., Frisina, R.D., Hamer, R.D. & Verrillo, R.T.   The Effects of a surround on vibrotactile thresholds.  Sensory Processes, 2, 99-115 (1979).

Gescheider, G.A., Frisina, R.D. & Verrillo, R.T. Selective adaptation of vibrotactile thresholds.  Sensory Processes, 3, 37-48 (1979)

Herrmann, D.J., Frisina, R.D. & Conti, G.  Categorization and familiarity in recognition involving a well-memorized list. J. Experimental PsychologyHuman Learning and Memory, 4, 428-440 (1978).

Frisina, R.D. and Gescheider, G.A. Comparison of child and adult vibrotactile thresholds as a function of frequency and duration.  Perception and Psychophysics, 22, 100-103 (1977).

 

PATENTS:      UNITED STATES –
Provisional: Sunol, A.K., Passaglia, C., Jacobson, T., Rogers, E., Guardiano, S., Ticknor, E., Cogswell, K., Frisina, R.D. (2015- In Prep) Bio-Medically Triggered Flotation Textile.

Provisional: Rigaud, E., Frisina, R.D., Bhethanabotla, V.R, Davis, G.R., Illig, K.A. (2015) Novel Guidewire Torque Device for Vascular Surgery.

Provisional: Bazard, P., Frisina, R.D., Walton, J.P., Bhethanabotla, V.R. (2015- In Prep) Plasmonic stimulation of electrically excitable biological cells.

Frisina, R.D., Walton, J.P., Ding, B., Zhu, X. (2015- Pending) Hormone Treatment for Age-Related Hearing Loss- Presbycusis.

Walton, J.P., Miller, K., Taylor, J., Fuller, L. & Frisina, R.D.  “Aid to Hearing Speech in a Noisy Environment”, Patent#: 5,285,502 (February 1994).

Miller, K., Fuller, L., Taylor, J., Frisina, R.D. & Walton, J.P.  “Hearing Aid with a Permanently-Adjusted Frequency Response”, Patent#:  5,406,633 (April, 1995).

PATENTS:      INTERNATIONAL –
Walton, J.P., Miller, K., Taylor, J., Fuller, L., & Frisina, R.D.  “Aid to Hearing Speech in a Noisy Environment”, Serial#: PCT/US 93908361.4 (1996).

 

BOOKS, REVIEWS, CHAPTERS, SHORT REPORTS & MONOGRAPHS:
Frisina, R.D. and D.R. Frisina (2016- In Press) Hormone Replacement Therapy and its Effects on Human Hearing.  In: Bass, A., Sisneros, J., Popper, A. & Fay, R.R. Eds.; Hearing & Hormones. Springer Science+Business Media, LLC, New York..

Frisina, R.D. and D.R. Frisina (2015) Genetics of Age-Related Hearing Loss.  In: J. Miller, C. Le Prell, L. Rybak, D. Armstrong, Eds.  Free Radicals in ENT Pathology: Oxidative Stress in Applied Basic Research and Clinical Practice.  Switzerland: Springer-International Press, Ch. 14.

Frisina, R.D. and D.R. Frisina (2013) Physiological and Neurobiological Bases of Age-Related Hearing Loss: Biotherapeutic Implications.  Am. J. Audiology.  22: 299-302.

Frisina, R.D. (2012) Hormones and Hearing: Too Much or Too Little of a Good Thing can be Ototoxic. Seminars in Hearing. 33: 231-241.

Frisina, R.D. (2010) Aging, Genetics and Central Auditory Neurobiology.  Audiology Today. Sep/Oct: 53-55.

Frisina, R.D., Zhu, X. and D’Souza, M. (2010) Biological Bases of Age-Related Hearing Loss.  Hearing Care for Adults 2009 – The Challenge of Aging, Proceedings of the Phonak Second International Adult Conference.

Frisina, R.D. (2010) Aging Changes in the Central Auditory System. In: Adrian Rees, Alan Palmer Eds.  Handbook of Auditory Science: The Auditory Brain. Oxford: Oxford University Press, Ch. 17, pp. 415-436.

*Frisina, R.D., Zhu, X. and D’Souza, M. (2010) Biological Bases of Age-Related Hearing Loss.  Phonak Proc. Int. Conf. Aging Auditory System, Ch. 2, pp. 19-24.

Gordon-Salant, S., Frisina, R.D., Popper, A. & Fay, R.R. (2010) The Aging Auditory System: Perceptual Characterization and Neural Bases of Presbycusis. New York: Springer-Verlag, 301 pp.

Gordon-Salant, S., Frisina, R.D. (2010) Introduction and Overview.  In: Gordon-Salant, S., Frisina, R.D., Popper, A. & Fay, R.R. Eds. The Aging Auditory System: Perceptual Characterization and Neural Bases of Presbycusis. New York: Springer-Verlag, Ch. 1.

Canlon, B. & Frisina, R.D. (2009) Sex Hormones and Hearing: A Pioneering Area of Enquiry,
Co-Editors, Special Issue of Hearing Research on Sex Hormones and Hearing, Vol. 252: 1-2. (PMCID: PMC2758054)

Frisina, R.D. (2009) Age-Related Hearing Loss: Ear and Brain Mechanisms.  Annals New York Academy of Sciences. 1170: 708–717.

*Vasilyeva, O.N., Frisina, S.T., Frisina, R.D. (2008) Multidisciplinary Studies Can Help Uncover Mechanisms of Age-Related Hearing Loss in Diabetics.  Hearing Health, Deafness Research Foundation, Summer, pp. 43-45.

Ohlemiller, K.K. & Frisina, R.D.  (2008) Clinical Characterization of Age-Related Hearing Loss and Its Neural and Molecular Bases.  In: J. Schacht, A. Popper, and R.R. Fay Eds.  Auditory Trauma, Protection and Treatment.  New York: Springer-Verlag. Ch. 6, pp.145-194.

Frisina, R.D.  (2007)  Hearing and Medicine as we Age. Am. Hearing Research Fn. Newsletter, 39.

Frisina, R.D. & D.R. Frisina (2006) Methods for Studying Hearing Impairment and Auditory Problems of the Aged.  In:  Michael Conn. Ed.  Handbook of Models for Human Aging.  Amsterdam: Elsevier, Ch. 76, pp. 911-922.

Frisina, R.D.  (2006)  Can we Identify Genes that Contribute to Age-Related Hearing Loss? Am. Hearing Research Foundation Newsletter, 38, 4.

Frisina, R.D.  (2006) Conversation – Age-related hearing loss.  Long-Term Care Interface, 7, 26-27.

Frisina, R.D. & Rajan, R.  (2005)  Inferior Colliculus: Aging and Plasticity.  In:  Winer J. and Schreiner, C. Eds.  The Inferior Colliculus.  New York: Springer, Ch. 18, pp. 559-584.

Frisina, R.D.  (2005)  Age-Related Hearing Loss: Can the Cochlear Battery be Recharged in Presbycusis. Am. Hearing Research Foundation Newsletter, 37, 2.

Frisina, D.R. & Frisina, R.D. (2005) The Neural and Genetic Bases of Age-Related Hearing Loss.  NTID Research Bulletin, 10:1-4.

*Frisina, R.D. & D’Souza, M. (2005) Optimizing Applications of Gene Expression Microarrays for Investigations of the Auditory System.  Assoc. Res. Otolaryngol. Short Course Handbook.

Frisina, R.D.  (2004)  Genetic Bases of Age-Related Hearing Loss – Presbycusis. Am. Hearing Research Foundation Newsletter, 33, 1-2.

Frisina, R.D.  (2004)  Molecular and Neural Perspectives on Age-Related Hearing Loss.  Am. Speech-Hearing-Language Assoc. Leader, July (2004), 16.

Frisina, R.D. (2001) Anatomical and neurochemical bases of presbycusis.  In: Hof PR, Mobbs CV, eds. Functional Neurobiology of Aging, San Diego: Academic Press, Ch. 37, pp 531-547.

Frisina, R.D. & Walton, J.P. (2001) Aging of the mouse central auditory system. In: Willott JF, ed.  Handbook of Mouse Auditory Res.: From Behavior to Molecular Biology.  Boca Raton, FL: CRC Press, pp 339-379, Ch. 24.

Frisina, R.D. & Walton, J.P. (2001) Neuroanatomy of the mouse central auditory system.  In: Willott JF, ed.  Handbook of Mouse Auditory Res.: From Behavior to Molecular Biology.  Boca Raton, FL: CRC Press, pp 243-277, Ch. 18.

Frisina, R.D. (2001) Possible neurochemical and neuroanatomical bases of age-related hearing loss - presbycusis.  Seminars In Hearing: Innovations in Aging Auditory Research 22:213-225

Ison, J.R., Walton, J.P., Frisina, R.D. & O’Neill, W.E. (2001) Elicitation and inhibition of the startle reflex by acoustic transients: Studies of age-related changes in temporal processing. In: Willott J.P., ed. Handbook of Mouse Auditory Res.: From Behavior to Molecular Biology. New York: CRC Press pp 381-387, Ch. 25.

Fong, C-T, Wang, M., Carter-Young, E., Hogan, C.A., Tallents, R.H., Kyrkanides, S., Liptak, G.S., Sanger, J.A., Frisina, R.D.  (2001)  Microtia associated with the Kabuki (Niikawa-Kuroki) syndrome.  Otolaryngology Head & Neck Surgery 125: 557-558.

Frisina, D.R., Frisina, R.D., Snell, K.B., Burkard, R., Walton, J.P. & Ison, J.R.  Auditory temporal processing during aging. In: Hof PR, Mobbs CV, eds. Functional Neurobiology of Aging. San Diego: Academic Press; (2001) Ch. 39, pp 565-579.

*Frisina, R.D., Wang, J., Byrd, J.D., Karcich, K.J. & Salvi, R.J.  Enhanced processing of temporal features of sounds in background noise by cochlear nucleus single neurons.  Proc. Prague Symposium on Acoustical Signal Processing in the Central Auditory System. J. Syka (Ed.) New York: Plenum Pub. (1997), Ch. 11, pp. 109-126.

Spongr, V.P., Walton, J.P., Frisina, R.D., Kazee, A.M., Flood, D.G. & Salvi, R.J.  Hair cell loss and synaptic loss in the inferior colliculus of C57B1/6 mice:  Relationship to abnormal temporal processing.  Proc. Prague Symposium on Acoustical Signal Processing in the Central Auditory System.  J. Syka (Ed.) New York: Plenum Pub. (1997), pp. 535-542.

*Byrd, J.D., Frisina, R.D. & Walton, J.P.  Superior olivary complex inputs to the dorsomedial inferior colliculus of the CBA mouse model of presbycusis remain stable with age.  Proc. Ninth Nat. Conf. Undergrad. Res. III, (1995) pp. 952-956.

Frisina, R.D., Walton, J.P. & Karcich, K.J.  Differential abilities to extract sound-envelope information by auditory nerve and cochlear nucleus neurons.  Sensory Research: Multimodal Perspectives.  R.T. Verrillo (Ed.) (Hillsdale, NJ:  Lawrence Erlbaum Assoc., Inc., 1993) Chapter 10, pp. 151-175.

Kauffman, W. & Frisina, R.D.  The fusion of neuroscience and music.  Psychomusicol. 11, 75-78 (1992).

Gulick, W.G., Gescheider, G.A. & Frisina, R.D. HEARING: Physiological Acoustics, Neural Coding, & Psychoacoustics.  (New York:  Oxford University Press, 1989) 409 p.
      
*Swartz, K.P., Hantz, E.C., Crummer, G.C., Walton, J.P. & Frisina, R.D.  Does the melody linger on?  Music cognition in Alzheimer's disease.  Seminars in Neurology 9, 152-158 (1989).

*O'Neill, W.E., Frisina, R.D., Gooler, D.M. & Zettel, M.L. Target range processing pathways in the auditory system of the mustached bat.  In: Animal Sonar: Processes and Performance. P. Nachtigall and P.W. B. Moore, Eds.  (New York: Plenum Publishing Corp., 1988) pp. 253-258.

Smith, R.L., Frisina, R.D. & Goodman, D. G.  Intensity Functions and dynamic responses from the cochlea to the cochlear nucleus.  In Hearing-Physiological Bases and Psychophysics. R. Klinke and R. Hartmann, Eds. (Berlin: Springer-Verlag, 1983) pp. 112-118.

Frisina, R.D.  Enhancement of responses to amplitude modulation in the gerbil cochlear nucleus:  Single-unit recordings using an improved surgical approach.  Special Report ISR-S-23.  Institute for Sensory Research, Syracuse University (1983), 203 pp.